发明名称 |
Therapy and diagnosis of conditions related to telomere length and/or telom erase activity |
摘要 |
Method and compositions are provided for the determination of telomere length and telomerase activity, as well as the ability to inhibit telomerase activity in the treatment of proliferative diseases. Particularly, primers are elongated under conditions which minimize interference from other genomic sequences, so as to obtain accurate determinations of telomeric length or telomerase activity. In addition, compositions are provided for intracellular inhibition of telomerase activity. |
申请公布号 |
AU8949698(A) |
申请公布日期 |
1999.01.14 |
申请号 |
AU19980089496 |
申请日期 |
1998.10.23 |
申请人 |
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO;UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS |
发明人 |
MICHAEL D. WEST;ELIZABETH H. BLACKBURN;WOODRING WRIGHT;JERRY SHAY |
分类号 |
C12N15/09;A61K31/70;A61K31/7088;A61K31/7105;A61K38/00;A61K38/43;A61K38/45;A61K38/55;A61K45/00;A61K48/00;A61K49/00;A61P35/00;A61P43/00;C12N5/00;C12N5/16;C12N9/12;C12N15/10;C12N15/113;C12Q1/25;C12Q1/48;C12Q1/68;C12Q1/70;G01N33/573 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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