ANTIOXIDANT ENHANCEMENT OF THERAPY FOR HYPERPROLIFERATIVE CONDITIONS
摘要
A method to enhance the cytotoxic activity of an antineoplastic drug comprising administering an effective amount of the antineoplastic drug to a host exhibiting abnormal cell proliferation in combination with an effective cytotoxicity-increasing amount of an antioxidant. The invention also includes a method to decrease the toxicity to an antineoplastic agent or increase the therapeutic index of an antineoplastic agent administered for the treatment of a solid growth of abnormally proliferating cells, comprising administering an antioxidant prior to, with, or following the antineoplastic treatment.
申请公布号
WO9901118(A2)
申请公布日期
1999.01.14
申请号
WO1998US13750
申请日期
1998.07.01
申请人
ATHEROGENICS, INC.;CHINERY, REBECCA;BEAUCHAMP, R., DANIEL;COFFEY, ROBERT, J.;MEDFORD, RUSSELL, M.;WADSINSKI, BRIAN
发明人
CHINERY, REBECCA;BEAUCHAMP, R., DANIEL;COFFEY, ROBERT, J.;MEDFORD, RUSSELL, M.;WADSINSKI, BRIAN