| 发明名称 |
CLONING PIGS USING DONOR NUCLEI FROM DIFFERENTIATED CELLS |
| 摘要 |
An improved method of nuclear transfer involving the transplantation of donor differentiated pig cell nuclei into enucleated pig oocytes is provided. The resultant nuclear transfer units are useful for multiplication of genotypes and transgenic genotypes by the production of fetuses and offspring. Production of genetically engineered or transgenic pig embryos, fetuses and offspring is facilitated by the present method since the differentiated cell source of the donor nuclei can be genetically modified and clonally propagated.
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| 申请公布号 |
CA2295294(A1) |
申请公布日期 |
1999.01.14 |
| 申请号 |
CA19982295294 |
申请日期 |
1998.07.01 |
| 申请人 |
UNIVERSITY OF MASSACHUSETTS, A PUBLIC INSTITUTION OF HIGHER EDUCATION OF THE COMMONWEALTH OF MASSACHUSETTS, AS REPRESENTED BY ITS AMHERST CAMPUS |
发明人 |
ROBL, JAMES M.;STICE, STEVEN L.;CIBELLI, JOSE;GOLUEKE, PAUL |
| 分类号 |
A01K67/02;A01K67/027;A61K35/12;A61K38/00;A61K48/00;A61P1/16;A61P1/18;A61P3/10;A61P9/00;A61P9/04;A61P13/02;A61P17/00;A61P17/02;A61P19/00;A61P21/00;A61P25/00;A61P25/16;A61P25/28;A61P31/18;A61P35/00;C12N5/073;C12N5/10;C12N15/09;C12N15/877;(IPC1-7):A01K67/027;A61K49/00;C12N5/00;C12N15/00;C12N15/87 |
主分类号 |
A01K67/02 |
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