发明名称 Boronic compound complexing reagents and complexes
摘要 Boron compound complexing reagents, boron compound complexes, and methods of synthesizing these reagents and complexes are disclosed. These reagents and complexes include those shown in General Formula IV and General Formula VI. In one embodiment, the reagent of General Formula IV may be used to form a complex with a boron compound, such as a complex shown in General Formula VI. <IMAGE> General Formula IV <IMAGE> General Formula VI In one embodiment, group Z comprises a spacer selected from a saturated or unsaturated chain of up to about 6 carbon equivalents in length, an unbranched saturated or unsaturated chain of from about 6 to 18 carbon equivalents in length with at least one of intermediate amide or disulfide moieties, and a polyethylene glycol chain of from about 3 to 12 carbon equivalents in length; group R3 is selected from one of an H, an alkyl, and a methylene or ethylene moiety with an electronegative substituent; and BAS and BAS* are biologically active species.
申请公布号 US5859210(A) 申请公布日期 1999.01.12
申请号 US19970956195 申请日期 1997.10.22
申请人 PROLINX, INC.;SYSTEMIX 发明人 STOWOLITZ, MARK L.;KAISER, ROBERT J.;LUND, KEVIN P.;TORKELSON, STEVEN M.
分类号 C07C229/38;C07C233/49;C07C233/51;C07C237/12;C07C237/22;C07C255/13;C07C259/10;C07C271/22;C07C281/02;C07D207/44;C07D207/452;C07D207/46;C07D213/71;C07F5/02;C07F5/04;C07K5/02;G01N33/543;(IPC1-7):C07F5/02 主分类号 C07C229/38
代理机构 代理人
主权项
地址