发明名称 |
Method for discovering novel anthelmintic compounds |
摘要 |
The present invention provides a novel radioactive neuropeptide represented by the formula Lys-His-Glu-Tyr-I-Leu-Arg-Phe-amide. The invention also provides a method for detecting anthelmintic activity of a compound using the novel neuropeptide of the present invention in a receptor binding assay. The novel radioactive neuropeptide has potent bioactivity in Ascaris suum neuromuscular strips, and therefore is particularly useful for high volume screening for potential anthelmintic compounds.
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申请公布号 |
US5859188(A) |
申请公布日期 |
1999.01.12 |
申请号 |
US19970866845 |
申请日期 |
1997.05.30 |
申请人 |
PHARMACIA & UPJOHN COMPANY |
发明人 |
GEARY, TIMOTHY G.;BOWMAN, JERRY W.;FRIEDMAN, ALAN R. |
分类号 |
G01N33/50;A61P33/10;C07K1/13;C07K7/06;C07K14/435;G01N33/15;(IPC1-7):A61K38/08 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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