发明名称 Method for discovering novel anthelmintic compounds
摘要 The present invention provides a novel radioactive neuropeptide represented by the formula Lys-His-Glu-Tyr-I-Leu-Arg-Phe-amide. The invention also provides a method for detecting anthelmintic activity of a compound using the novel neuropeptide of the present invention in a receptor binding assay. The novel radioactive neuropeptide has potent bioactivity in Ascaris suum neuromuscular strips, and therefore is particularly useful for high volume screening for potential anthelmintic compounds.
申请公布号 US5859188(A) 申请公布日期 1999.01.12
申请号 US19970866845 申请日期 1997.05.30
申请人 PHARMACIA & UPJOHN COMPANY 发明人 GEARY, TIMOTHY G.;BOWMAN, JERRY W.;FRIEDMAN, ALAN R.
分类号 G01N33/50;A61P33/10;C07K1/13;C07K7/06;C07K14/435;G01N33/15;(IPC1-7):A61K38/08 主分类号 G01N33/50
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