发明名称 |
Pharmaceutical composition for cyclosporines |
摘要 |
The invention comprises a stable solution of cyclosporine forming a polar lipid self-emulsifying drug delivery system ("PLSEDDS"). The composition typically consists of cyclosporine dissolved in a polar lipid, such as a medium chain monoglyceride of C6-C12 fatty acids having a monoglyceride content of at least 50% and a surfactant. The composition provided here instantly forms a fine emulsion on exposure to water. The encapsulated dosage form of this composition needs neither a hydrophilic component nor air-tight blister packaging, and is particularly suitable for oral administration.
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申请公布号 |
US5858401(A) |
申请公布日期 |
1999.01.12 |
申请号 |
US19970786314 |
申请日期 |
1997.01.22 |
申请人 |
SIDMAK LABORATORIES, INC. |
发明人 |
BHALANI, VINAYAK T.;PATEL, SATISHCHANDRA P. |
分类号 |
A61K9/107;A61K9/48;(IPC1-7):A61K9/48 |
主分类号 |
A61K9/107 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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