发明名称 |
Liposomal formulations of mitoxantrone |
摘要 |
Compositions and methods which are useful for the treatment of solid tumors in a host and which are also useful for increasing the therapeutic index of mitoxantrone in a host. The pharmaceutical compositions are liposomal formulations of mitoxantrone in which the liposomes comprise a mixture of cholesterol and a diacylphosphatidylcholine, preferably 1,2-sn-dimyristoyl-phosphatidylcholine.
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申请公布号 |
US5858397(A) |
申请公布日期 |
1999.01.12 |
申请号 |
US19950542341 |
申请日期 |
1995.10.11 |
申请人 |
UNIVERSITY OF BRITISH COLUMBIA |
发明人 |
LIM, HOWARD J.;MADDEN, THOMAS D.;BALLY, MARCEL B.;BARBER, LANA W.;CHANG, CHARMAINE W. |
分类号 |
A61K9/127;A61K31/135;A61K31/136;A61K31/137;A61K47/10;A61K47/24;(IPC1-7):A61K9/127 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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