MEASURING MOLECULAR CHANGE IN THE OCULAR LENS

摘要

Apparatus and methods for noninvasively diagnosing diabetes mellitus, the prediabetic condition, cataracts, and other diseases in the human (or other) body are disclosed. Diagnoses are made by illuminating ocular lens (L) or other tissue with a narrowband light source (15) at a selected wavelength, separating the backscattered radiation into fluorescent and Rayleigh components (55, 135), detecting (85) the backscattered radiation intensity at the peak of the fluorescent response, and normalizing the detected value with the detected intensity of its Rayleigh component. Measurements provided in this manner can be used as improved indicators of the presence or absence of certain diseases or conditions.