摘要 |
FIELD: medicine. SUBSTANCE: novel chemical compounds, more particularly beta- hydroethylaminium-5- hydroxynicotinates of formula I: beta wherein R is CH<SB>2</SB>CH<SB>2</SB>OH(XC-1), CH<SB>3</SB>(XC-2), H(XC-3), said compounds have antiischemic activity. Desired compounds are prepared by reacting 5- hydroxynicotinic acid with corresponding aminoalkyls in the presence of solvent during heating operation. In experiments on animals, said compounds show high antiischemic activity and low toxicity. EFFECT: improved properties of the title compounds. 2 ex, 4 tbl
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