| 发明名称 |
TIOESTERES Y CETONAS HETEROCICLICOS |
| 摘要 |
This invention relates to neurotrophic low molecular weight, small molecule heterocyclic thioesters having an affinity for FKBP-type immunophilines, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme acitivity.
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| 申请公布号 |
PE110498(A1) |
申请公布日期 |
1999.01.10 |
| 申请号 |
PE19970000861 |
申请日期 |
1997.09.24 |
| 申请人 |
GUILFORD PHARMACEUTICALS INC. |
发明人 |
HAMILTON, GREGORY S.;LI, JIA-HE |
| 分类号 |
C07D207/16;A61K31/40;A61K31/404;A61K31/4439;A61K31/445;A61P25/16;A61P25/28;C07D207/06;C07D207/08;C07D211/22;C07D211/30;C07D211/32;C07D211/60;C07D401/06;C07D401/12;C07D403/12 |
主分类号 |
C07D207/16 |
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