发明名称 |
Method for producing fumaric acid |
摘要 |
<p>Fumaric acid is produced by reacting maleic acid in an aqueous solution with a microorganism which has maleate isomerase activity or with a preparation from the microorganism having the maleate isomerase activity, and producing fumaric acid in a reaction solution by enzymatic isomerization of maleic acid carried out under the condition that the dissolved oxygen concentration in the reaction solution is substantially maintained at 4 ppm or less, for example, by sealing the reaction solution with one or more gases selected from N2, Ar, and He.</p> |
申请公布号 |
EP0736603(B1) |
申请公布日期 |
1999.01.07 |
申请号 |
EP19960105368 |
申请日期 |
1996.04.03 |
申请人 |
MITSUBISHI CHEMICAL CORPORATION |
发明人 |
GOTO, MAKOTO;TOKUMARU, IZURU;TERASAWA, MASATO;YUKAWA, HIDEAKI |
分类号 |
C12P7/46;C12P13/20;(IPC1-7):C12P7/46 |
主分类号 |
C12P7/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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