| 摘要 |
The invention relates to compounds of formula (I), wherein aArg, aGly, aAsp, aX and aY have the meaning cited in Claim 1, and to the salts thereof. The inventive compounds can be used as integrin inhibitors, specially in the prophylaxis and treatment of circulatory diseases, thrombosis, infarcts, coronary heart diseases, arteriosclerosis, pathological conditions, which are maintained or propagated by angiogenesis, and in addition to tumor therapy. |
| 申请人 |
MERCK PATENT GMBH, 64293 DARMSTADT, DE |
发明人 |
JONCZYK, ALFRED, DR., 64295 DARMSTADT, DE;GOODMAN, SIMON L., DR., 64287 DARMSTADT, DE;KESSLER, HORST, PROF. DR., 65824 SCHWALBACH, DE;WERMUTH, JOCHEN, DR., 85095 DENKENDORF, DE;SCHMITT, JOERG, 85748 GARCHING, DE |
