| 摘要 |
A topical insect repellent with extended duration of protection was obtained from mixtures of molecules based on two or more volatile repellent organic molecular species occurring naturally on the human skin surfaces. The novel repellent comprises mixtures of lower, intermediate, and higher volatility organic molecules. Active ingredients for formulations are obtained from homologous series of carboxylic acids, alcohols, ketones and lactones which span a similar range of volatility and which occur naturally on the skin surface. Volatile silicone fluid imparts mildness and water repellency to the repellent formulations. The invention repellent exhibits longevity and repellency that is comparable to DEET. The invention repellent, formulated in a volatile silicone fluid, was shown to repel and incapacitate stable flies. Repellency extends to mosquitoes and other biting flies or insects.
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