发明名称 |
NOVEL BENZIMIDAZOL TRICYCLIC DERIVATIVES, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
摘要 |
The invention concerns derivatives of general formula (I) in which: n is equal to 0, 1 or 2; R1 represents: a -(CH2)m-CO-R5 group with m ranging between 0 and 6 and R5 represents an alkyl, cycloalkyl, bicycloalykl, tricycloalkyl, hydroxyl, alkoxy, amino; an amino group optionally substituted, and in this case, X and R2 form a bond; or R2 represents a -(CH2)m-COR5 group, as defined above or an amino group optionally substituted, and in this case, X and R1 form a bond; R3 and R4 represent a hydrogen, halogen, an alkyl, hydroxy, alkoxy or trihalogenoalkyl group. The invention is useful for treating diabetes and/or cardiovascular disorders.
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申请公布号 |
WO9900390(A1) |
申请公布日期 |
1999.01.07 |
申请号 |
WO1998FR01309 |
申请日期 |
1998.06.23 |
申请人 |
ADIR ET COMPAGNIE;ANISIMOVA, VERA A.;OSIPOVA, MARINA M.;KUZMENKO, TATIANA A.;CAIGNARD, DANIEL-HENRI;RENARD, PIERRE;MANECHEZ, DOMINIQUE |
发明人 |
ANISIMOVA, VERA A.;OSIPOVA, MARINA M.;KUZMENKO, TATIANA A.;CAIGNARD, DANIEL-HENRI;RENARD, PIERRE;MANECHEZ, DOMINIQUE |
分类号 |
C07D487/04;(IPC1-7):C07D487/04;A61K31/415;A61K31/505;A61K31/55 |
主分类号 |
C07D487/04 |
代理机构 |
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地址 |
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