发明名称 NOVEL BENZIMIDAZOL TRICYCLIC DERIVATIVES, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 The invention concerns derivatives of general formula (I) in which: n is equal to 0, 1 or 2; R1 represents: a -(CH2)m-CO-R5 group with m ranging between 0 and 6 and R5 represents an alkyl, cycloalkyl, bicycloalykl, tricycloalkyl, hydroxyl, alkoxy, amino; an amino group optionally substituted, and in this case, X and R2 form a bond; or R2 represents a -(CH2)m-COR5 group, as defined above or an amino group optionally substituted, and in this case, X and R1 form a bond; R3 and R4 represent a hydrogen, halogen, an alkyl, hydroxy, alkoxy or trihalogenoalkyl group. The invention is useful for treating diabetes and/or cardiovascular disorders.
申请公布号 WO9900390(A1) 申请公布日期 1999.01.07
申请号 WO1998FR01309 申请日期 1998.06.23
申请人 ADIR ET COMPAGNIE;ANISIMOVA, VERA A.;OSIPOVA, MARINA M.;KUZMENKO, TATIANA A.;CAIGNARD, DANIEL-HENRI;RENARD, PIERRE;MANECHEZ, DOMINIQUE 发明人 ANISIMOVA, VERA A.;OSIPOVA, MARINA M.;KUZMENKO, TATIANA A.;CAIGNARD, DANIEL-HENRI;RENARD, PIERRE;MANECHEZ, DOMINIQUE
分类号 C07D487/04;(IPC1-7):C07D487/04;A61K31/415;A61K31/505;A61K31/55 主分类号 C07D487/04
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