HELICOBACTER ALIPHATIC AMIDASE AMIE POLYPEPTIDES, AND DNA SEQUENCES ENCODING THOSE POLYPEPTIDES

摘要

This invention relates to Helicobacter species aliphatic amidase AmiE polypeptides, the DNA encoding those polypeptides and transformed microorganisms capable of expressing those polypeptides. This invention also relates to the use of Helicobacter sp. (particularly Helicobacter pylori) amidase AmiE polypeptides and antibodies specific for those polypeptides in immunogenic, therapeutic, and diagnostic applications. The invention additionally relates to processes of producing Helicobacter species aliphatic amidase AmiE polypeptides and intermediates useful in the production of those polypeptides.