发明名称 Processes for preparing azepiones useful as intermediates in the preparation of inhibitors of angiotensin converting enzyme and neutral endopeptidase
摘要 Processes are disclosed for preparing the azepine intermediates of the formula <IMAGE> These intermediates can be reacted with acylmercaptocarboxylic acids of the formula <IMAGE> to give the pharmaceutically active products.
申请公布号 US5856476(A) 申请公布日期 1999.01.05
申请号 US19970946938 申请日期 1997.10.08
申请人 E. R. SQUIBBS & SONS, INC. 发明人 ROBL, JEFFREY A.
分类号 A61K38/00;C07D223/12;C07D223/16;C07D225/06;C07D267/14;C07D279/06;C07D281/06;C07D281/10;C07D471/04;C07D487/04;C07D513/04;C07K5/078;(IPC1-7):C07D223/10;C07D225/02;C07D211/76 主分类号 A61K38/00
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