发明名称 |
Processes for preparing azepiones useful as intermediates in the preparation of inhibitors of angiotensin converting enzyme and neutral endopeptidase |
摘要 |
Processes are disclosed for preparing the azepine intermediates of the formula <IMAGE> These intermediates can be reacted with acylmercaptocarboxylic acids of the formula <IMAGE> to give the pharmaceutically active products.
|
申请公布号 |
US5856476(A) |
申请公布日期 |
1999.01.05 |
申请号 |
US19970946938 |
申请日期 |
1997.10.08 |
申请人 |
E. R. SQUIBBS & SONS, INC. |
发明人 |
ROBL, JEFFREY A. |
分类号 |
A61K38/00;C07D223/12;C07D223/16;C07D225/06;C07D267/14;C07D279/06;C07D281/06;C07D281/10;C07D471/04;C07D487/04;C07D513/04;C07K5/078;(IPC1-7):C07D223/10;C07D225/02;C07D211/76 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|