发明名称 Method to enhance innate immunity defense mechanisms by treatment with plant-derived alkaloids
摘要 The present invention relates to a method for enhancing innate immunity defense mechanisms of vertebrate animals including humans. In accordance with the present invention, innate immunity defenses are enhanced by the administration of plant-derived immunomodulators. These plant-derived immunomodulators may be plant tissues, plant extracts containing steroid-like glycoalkaloids, or plant-derived glycoalkaloids. The administration of these immunomodulators significant augments the antimicrobial activities of the innate immune system. The glycoalkaloids useful for the present invention have the formula R-R1, wherein R is a mono-, di-, tri- or oligo-saccharide which may optionally be modified with pharmacologically acceptable esters or ethers and R1 is an aglycon or derivative as defined herein. Preferred plant-derived glycoalkaloids include solanine and chaconine.
申请公布号 AU7980098(A) 申请公布日期 1999.01.04
申请号 AU19980079800 申请日期 1998.06.19
申请人 MICHAEL J. GUBAREV;ELENA Y. ENIOUTINA 发明人 MICHAEL J. GUBAREV;ELENA Y. ENIOUTINA
分类号 A61K31/56;A61K31/58;A61K36/81;A61K36/896 主分类号 A61K31/56
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