| 发明名称 |
Inhibitors of alpha<sub>4</sub>beta<sub>1</sub>mediated cell adhesion |
| 摘要 |
The present invention relates to small molecules according to the formula [I]:which are potent inhibitors of alpha4beta1 mediated adhesion to either VCAM or CS-1 and which can be used for treating or preventing alpha4beta1 adhesion mediated conditions in a mammal such as a human. |
| 申请公布号 |
AU8163398(A) |
申请公布日期 |
1999.01.04 |
| 申请号 |
AU19980081633 |
申请日期 |
1998.06.23 |
| 申请人 |
TANABE SEIYAKU CO., LTD.;PHARMACIA & UPJOHN COMPANY |
发明人 |
THOMAS J. LOBL;GIL RISHTON;BRADLEY TEEGARDEN;ALEX POLINSKY;MASAFUMI YAMAGISHI;STEVEN P. TANIS;JED F. FISHER;EDWARD W. THOMAS;ROBERT A CHRUSCIEL |
| 分类号 |
C07D295/18;A61K31/198;A61K31/223;C07C229/46;C07C233/60;C07C233/63;C07C233/81;C07C233/83;C07C233/87;C07C235/40;C07C235/64;C07C235/84;C07C237/22;C07C237/40;C07C237/42;C07C255/29;C07C255/46;C07C259/08;C07C271/22;C07C271/28;C07C275/26;C07C275/42;C07C311/21;C07C311/64;C07D207/16;C07D209/20;C07D209/22;C07D213/64;C07D213/81;C07D213/82;C07D217/26;C07D233/24;C07D233/54;C07D233/64;C07D295/185;C07D295/192;C07D307/68;C07D333/24 |
主分类号 |
C07D295/18 |
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