发明名称 |
Cd154 blockade therapy for pancreatic islet tissue transplantation |
摘要 |
Methods and compositions for inhibiting rejection of insulin-producing tissue in a graft recipient, as well as methods and compositions for prolonging graft survival or function; for reversing graft rejection or restoring function of an impaired graft; and, for inducing immunological tolerance to grafted, insulin-producing tissue. The present methods and compositions are suitable for treatment or prophylaxis of defects in metabolic control of blood glucose homeostasis, including defects manifested as diabetes mellitus (DM). |
申请公布号 |
AU7983098(A) |
申请公布日期 |
1999.01.04 |
申请号 |
AU19980079830 |
申请日期 |
1998.06.19 |
申请人 |
BIOGEN, INC.;UNIVERSITY OF MIAMI |
发明人 |
NORMA S. KENYON;CAMILLO RICORDI;DAVID W THOMAS;LINDA BURKLY |
分类号 |
A61K39/395;A61K35/28;A61K38/00;A61P3/08;A61P3/10;A61P37/06;C07K16/28 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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