发明名称 |
Crystalline roxifiban |
摘要 |
The potent platelet glycoprotein IIb/IIIa antagonist, roxifiban, is produced in crystalline form. Crystalline roxifiban exists in two polymorphic forms, designated Form 1 and Form 2. These polymorphic forms are characterized by x-ray powder diffraction and solid-state carbon NMR. Pharmaceutical compositions and methods for the treatment or prevention of diseases mediated by platelet aggregation are described. |
申请公布号 |
AU8071998(A) |
申请公布日期 |
1999.01.04 |
申请号 |
AU19980080719 |
申请日期 |
1998.06.12 |
申请人 |
THE DU PONT MERCK PHARMACEUTICAL COMPANY |
发明人 |
MICHAEL B. MAURIN;PHILIP MA;DAVID J. MELONI;JAAN A. PESTI;LUCIUS T. ROSSANO;RANDALL K. WARD;JIANGUO YIN;LIN-HUA ZHANG |
分类号 |
A61K31/42;A61P1/04;A61P7/02;A61P9/10;A61P11/06;A61P19/02;A61P19/10;A61P29/00;A61P35/04;A61P37/08;A61P43/00;C07D261/04 |
主分类号 |
A61K31/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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