PROCESS FOR THE PREPARATION OF HALOGENATED HYDROXY DIPHENYL COMPOUNDS.

摘要

A 4-stage preparation of halogenated diphenyl ethers of formula (1) is claimed, as are also (A) novel compounds of formula (8a) (ie certain of the oxidised intermediates of formula (8)) and (B) the use of the compounds thus obtained as disinfectants to protect organic materials against attack by microorganisms. The preparation (shown in the reaction scheme below) comprises (i) acylating a halogenated benzene compound of formula (4); (ii) etherifying with a halogenated phenol (6); (iii) oxidising the ether ((7); and (iv) hydrolysing the oxidation product (8). In (1); R1 and R2 = F, Cl or Br; R3 and R4 = H or 1-4C alkyl; m = 1-3; and n = 1 or 2. In (8a) R'1, R'2 and R'3 = F, Cl or Br; and R'4 and R'5 = H or 1-5C alkyl.