发明名称 (S)-(-)-N-[3- [5-[(4-FLUOROPHENYL)METHYL] -2-THIENYL]-1-METHYL -2-PROPYNYL]-N-HYDROXYUREA
摘要 <p>Methods utilizing optically pure S761 for the treatment of asthma, allergic rhinitis, psoriasis and inflammatory bowel disease while substantially reducing the concomitant liability of adverse effects associated with the corresponding R enantiomer and the racemic mixture. S761 is an inhibitor of 5-lipoxygenase and is therefore useful in the treatment of other conditions related to elevated leukotriene levels. Its structure is formula (I).</p>
申请公布号 WO1998058645(A1) 申请公布日期 1998.12.30
申请号 US1998012847 申请日期 1998.06.19
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