(S)-(-)-N-[3- [5-[(4-FLUOROPHENYL)METHYL] -2-THIENYL]-1-METHYL -2-PROPYNYL]-N-HYDROXYUREA

摘要

Methods utilizing optically pure S761 for the treatment of asthma, allergic rhinitis, psoriasis and inflammatory bowel disease while substantially reducing the concomitant liability of adverse effects associated with the corresponding R enantiomer and the racemic mixture. S761 is an inhibitor of 5-lipoxygenase and is therefore useful in the treatment of other conditions related to elevated leukotriene levels. Its structure is formula (I).