| 摘要 |
<p>Quinolone derivatives represented by general formula (I), salts thereof, and hydrates thereof of both, having potent antimicrobial activities against various bacteria including resistant strains and being highly safe: wherein R1 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms; R2 represents a halogenomethoxyl or alkoxyl group; R3 represents an alkyl, alkenyl, halogenoalkyl, cyclic alkyl, heteroaryl, alkoxyl, or alkylamino group; R4 represents a hydrogen atom or a phenyl, acetoxymethyl, pivaloyloxymethyl, ethoxycarbonyl, choline, dimethylaminoethyl, 5-indanyl, phthalidinyl, 5-alkyl-2-oxo-1,3-dioxol-4-ylmethyl, 3-acetoxy-2-oxobutyl, alkyl, alkoxymethyl, or phenylalkyl group. The above substituents may be further substituted.</p> |
