发明名称 SOLUBLE PRODRUGS OF PACLITAXEL
摘要 <p>Novel 2'-onium salts of paclitaxel act as prodrugs in mammalian patients to yield paclitaxel in vivo. Methods of synthesizing these onium salts are disclosed, as are methods of treating patients suffering from paclitaxel-responsive diseases by administering effective amounts of the onium salts and pharmaceutical compositions containing the novel salts which are suitable for administration to patients requiring paclitaxel therapy.</p>
申请公布号 WO1998058927(A1) 申请公布日期 1998.12.30
申请号 US1997010746 申请日期 1997.06.20
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