The present invention relates to novel vaccines for the prevention or attenuation of Lyme disease. The invention further relates to isolated nucleic acid molecules encoding antigenic polypeptides of Borrelia burgdorferi. Antigenic polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. The invention additionally relates to diagnostic methods for detecting Borrelia gene expression.
申请公布号
CA2294568(A1)
申请公布日期
1998.12.30
申请号
CA19982294568
申请日期
1998.06.18
申请人
HUMAN GENOME SCIENCES, INC.;MEDIMMUNE, INC.
发明人
ERWIN, ALICE L.;CHOI, GIL H.;LATHIGRA, RAJU;HANSON, MARK S.