摘要 |
<p>Methods utilizing optically pure A-79176 for the treatment of asthma, allergic rhinitis, psoriasis and inflammatory bowel disease while substantially reducing the concomitant liability of adverse effects associated with the corresponding R enantiomer and the racemic mixture. A-79176 is an inhibitor of 5-lipoxygenase and is therefore useful in the treatment of other conditions related to elevated leukotriene levels. Its structure is (I).</p> |