TRIAZOLO-1,4-DIAZEPINE COMPOUNDS AND MEDICINAL COMPOSITION CONTAINING THE SAME

摘要

Triazolo-1,4-diazepine compounds represented by general formula (I) and combining a PAF antagonism with a thromboxane synthesis inhibitory activity; and a medicine containing the same as the active ingredients wherein A represents CO, CO-B, or B, where B represents C1-6 alkylene or C2-6 alkylene interposed by an oxygen atom; X represents N-O or CH; n is an integer of 2 to 6; R represents hydroxy or C1-6 alkyloxy or alkylamino (optionally substituted by N,N-dimethylamino, N,N-diethylamino, phenyl, or heterocycle); and R1 represents hydrogen or C1-3 alkyl.