摘要 |
PCT No. PCT/US93/09407 Sec. 371 Date May 25, 1995 Sec. 102(e) Date May 25, 1995 PCT Filed Oct. 7, 1993 PCT Pub. No. WO94/13663 PCT Pub. Date Jun. 23, 1994A compound of the formula <IMAGE> or a pharmaceutically acceptable salt thereof; W is hydrogen, (C1-C6)alkyl optionally substituted with from one to three fluorine atoms, -S(O)v-(C1-C6) alkyl wherein v is zero, one or two, halo, benzyloxy or (C1-C6)alkoxy optionally substituted with from one to three fluorine atoms; R1 is a 4, 5 or 6 membered heterocyclic ring containing from one to three heteroatoms selected from oxygen, nitrogen and sulfur, wherein said heterocyclic ring contains from zero to three double bonds and is optionally substituted with one or two substituents independently selected from (C1-C6) alkyl optionally substituted with from one to three fluorine atoms and (C1-C6) alkoxy optionally substituted with from one to three fluorine atoms; R2 is hydrogen or -CO2(C1-C10)alkyl; R3 is <IMAGE> VII
|