The invention relates to a pharmaceutical preparation containing or consisting of the following components: (i) an initial dose of active agent containing the active agent and optional auxiliary agents (ii) a first type of controlled release pellet in which the active agent and the optional auxiliary agents are coated, and (iii) a second type of controlled release pellet in which the active agent and optional auxiliary agents are also coated. The active agent is an ACE inhibitor and the weight ratio of the masses of the coatings in (ii) and (iii) is between 1:2 and 1:7.
