发明名称 ELEVATION OF HDL CHOLESTEROL BY 2-(4-CHLORO -1-ARYL-BUTYLIDENE) -HYDRAZINECARBOTHIOAMIDES
摘要 <p>This invention relates to the treatment of atherosclerosis via raising the level of HDL cholesterol by administration of a compound of formula (I), wherein R?1, R2 and R3¿ are independently hydrogen, C¿1?-C10 alkyl, or -(CH2)0-6Ar?1¿ where Ar1 is phenyl, furanly, pyridinyl or thienyl, and Ar1 is optionally substituted by halogen, cyano, nitro, C¿1?-C6 alkyl, C1-C6 alkoxy, trifluoromethyl, C1-C6 alkoxycarbonyl, -CO2H or OH.</p>
申请公布号 WO1998057928(A1) 申请公布日期 1998.12.23
申请号 US1998010461 申请日期 1998.05.19
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