THERAPEUTIC COMPOSITION

摘要

A fast-release homogeneous compressed tablet composition comprising: (i) 1-50 % by weight flurbiprofen or a pharmaceutically acceptable salt thereof; and (ii) 50-99 % by weight compressible carrier material comprising a disintegrant and a compressible component selected from a sugar component, a starch component and an alkaline earth metal component; characterised in that the compressible carrier material further comprises microcrystalline cellulose present in a ratio to said compressible component of 1:4 to 4:1 parts by weight; and further characterised in that the crushing strength of the tablet is in the range 5-15 Kgf and that the disintegration time is less than 10 minutes.