发明名称 |
23 OR 24 DAY CONTRACEPTIVE FORMULATION COMPRISING BOTH AN ESTROGEN AND A GESTAGEN, ADMINISTERED IN CONSTANT AMOUNTS THROUGHOUT THE 23 OR 24 DAYS |
摘要 |
<p>Conception is prevented in a fertile female who has not reached the pre-menopause by the admin. over a 28 day cycle of a combination of: (a) an estrogen content comprising: 2-6 mg 17beta -oestradiol or 0.015-ethynyloestradiol; and (b) a gestagen content comprising: 0.05-0.075 mg gestodene; 0.075-0.125 mg levonorgestrel; 0.06-0.15 mg desogestrel or 3-ketodesogestrel; 0.1-0.3 mg drospirenone; 0.1-0.2 mg cyproterone acetate; 0.2-0.3 mg norgestimate or > 0.35 mg to 0.75 mg norethisterone; for 23 or 24 days commencing on day 1 of the menstruation cycle followed by 5 or 4 days without this medication or with a placebo. Also claimed is a contraceptive pack contg. 23 or 24 dosage units contg. the oestrogen and gestagen components and 5 or 4 placebos or other instructions to the effect that 5 or 4 days without medicament or with placebo should follow the admin. of a dosage unit for 23 or 24 consecutive days; with the estrogen content being: > 2 mg to 6 mg oestradiol or 0.02 mg ethynyloestradiol; and the gestagen content being: above 0.06-0.075 mg gestodene, > 0.1-0.125 mg levonorgestrel, > 0.1-0.15 mg desogestrel or 3-ketodesogestrel, 0.25-0.3 mg drospirenone, 0.1-0.2 mg cyproterone acetate, 0.2-0.3 mg norgestimate or 0.5-0.75 mg norethisterone.</p> |
申请公布号 |
NZ278058(A) |
申请公布日期 |
1998.12.23 |
申请号 |
NZ19940278058 |
申请日期 |
1994.12.22 |
申请人 |
SCHERING AG |
发明人 |
SPONA, JURGEN;DUSTERBERG, BERND;LUDICKE, FRANK;FEICHTINGER,W;ELSTEIN, MAX |
分类号 |
A61K31/565;A61K31/57;A61K31/58;A61P15/18;(IPC1-7):A61K31/57 |
主分类号 |
A61K31/565 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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