A METHOD OF ENHANCING ANTIGEN-SPECIFIC PERIPHERAL IMMUNE TOLERANCE

摘要

There is disclosed a method of initiating or enhancing antigen-specific immune tolerance by administering an effective amount of flt3-ligand prior to, concurrent with, or subsequent to the mucosal administration of an immunotolerizing amount of the immunogenic molecule. Tolerance can be initiated or enhanced to angitens associated with autoimmune diseases, organ or tissue transplantation, food allergies, and immunogenic therapeutic products.