发明名称 COUP-TFII: AN ORPHAN NUCLEAR RECEPTOR REQUIRED FOR ANGIOGENESIS
摘要 The COUP-TFII gene is essential for angiogenesis. The present invention exploits the role of the COUP-TFII receptor in angiogenesis by the selective use of agonists and antagonists to manipulate angiogenesis. Using agonists of COUP-TFII, angiogenesis can be enhanced, making the agonist a suitable treatment for wounds, promoting recovery from skin-graft surgery and organ transplants. Using COUP-TFII antagonists, angiogenesis can be inhibited, which makes it a suitable treatment for tumor inhibition.
申请公布号 WO9857647(A1) 申请公布日期 1998.12.23
申请号 WO1998US12504 申请日期 1998.06.16
申请人 BAYLOR COLLEGE OF MEDICINE;TSAI, MING-JER;TSAI, SOPHIA, Y.;QIU, YUHONG;PEREIRA, FREDRICK, A.;O'MALLEY, BERT, W.;DEMAYO, FRANCESCO 发明人 TSAI, MING-JER;TSAI, SOPHIA, Y.;QIU, YUHONG;PEREIRA, FREDRICK, A.;O'MALLEY, BERT, W.;DEMAYO, FRANCESCO
分类号 A61K31/00;(IPC1-7):A61K31/59;A61K31/56 主分类号 A61K31/00
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