发明名称 |
EXPRESSION SYSTEM FOR PRODUCTION OF THERAPEUTIC PROTEINS |
摘要 |
A novel method is described for expressing biologically functional therapeutic proteins without host cell toxicity. This method takes advantage of the surprising replication activitating ability of the 107/402-T antigen. The invent ion also provides expression vectors, human cells, and fusion proteins for practicin g the method. The invention thus provides the art with an expression system for therapeutic proteins which is useful to the pharmaceutical and biotechnology industries.
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申请公布号 |
CA2218852(A1) |
申请公布日期 |
1998.12.20 |
申请号 |
CA19972218852 |
申请日期 |
1997.12.18 |
申请人 |
CASE WESTERN RESERVE UNIVERSITY |
发明人 |
BRUNOVSKIS, PETER;COOPER, MARK J. |
分类号 |
C12N15/09;A61K35/12;A61K35/28;A61K48/00;C07K14/025;C07K14/72;C07K19/00;C12N5/10;C12P21/02;C12R1/91;(IPC1-7):C12N15/69;C12N15/12;C12N15/37;C12N15/62;C12N15/85 |
主分类号 |
C12N15/09 |
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