发明名称 EXPRESSION SYSTEM FOR PRODUCTION OF THERAPEUTIC PROTEINS
摘要 A novel method is described for expressing biologically functional therapeutic proteins without host cell toxicity. This method takes advantage of the surprising replication activitating ability of the 107/402-T antigen. The invent ion also provides expression vectors, human cells, and fusion proteins for practicin g the method. The invention thus provides the art with an expression system for therapeutic proteins which is useful to the pharmaceutical and biotechnology industries.
申请公布号 CA2218852(A1) 申请公布日期 1998.12.20
申请号 CA19972218852 申请日期 1997.12.18
申请人 CASE WESTERN RESERVE UNIVERSITY 发明人 BRUNOVSKIS, PETER;COOPER, MARK J.
分类号 C12N15/09;A61K35/12;A61K35/28;A61K48/00;C07K14/025;C07K14/72;C07K19/00;C12N5/10;C12P21/02;C12R1/91;(IPC1-7):C12N15/69;C12N15/12;C12N15/37;C12N15/62;C12N15/85 主分类号 C12N15/09
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