| 摘要 |
A method of testing an individual predisposed to or who may be at possible risk of developing a complex polygenic disease including but not restricted to coronary artery disease, essential hypertension, hyperlipidemia, non-insulin dependent diabetes mellitus, or diabetic neuropathy to ascertain whether there is an elevation in their risk of acquiring one or more of these conditions, the method comprising determination of the genotype of the individual for a polymorphism in the tumor necrosis factor receptor superfamily member 1B gene that encodes tumor necrosis factor receptor 2, wherein the presence of one allele of the polymorphism is indicative of an increased risk over an individual with a contrasting allele of the polymorphism. |
