发明名称 |
STABLE INSULIN FORMULATIONS |
摘要 |
The present invention provides a monomeric insulin analog formulation stabilized against aggregation in which the buffering agent is either TRIS or arginine. The stable formulations of the present invention are useful for treating diabetes, and are particularly advantageous in treatment regimes requiring lengthy chemical and physical stability, such as, in continuous infusion systems.
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申请公布号 |
CA2295140(A1) |
申请公布日期 |
1998.12.17 |
申请号 |
CA19982295140 |
申请日期 |
1998.06.11 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
DEFELIPPIS, MICHAEL ROSARIO;DOBBINS, MICHAEL ALLEN;LI, SHUN;REBHUN, DAWN MARIE;FRANK, BRUCE HILL |
分类号 |
A61K9/08;A61K38/28;A61K47/02;A61K47/10;A61K47/16;A61K47/18;A61P3/10;(IPC1-7):A61K38/28 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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