COMPOSITION AND METHOD TO PREVENT GRAFT REJECTION AND OTHER COUNTER-ADAPTIVE T LYMPHOCYTE MEDIATED IMMUNE RESPONSES

摘要

A method is provided for preventing and reversing acute allograft rejection wherein both the CD80/CD86:CD28/CTLA-4 interaction and the CD40:CD154 interaction are interrupted. The effect of the method on treating autoimmune diseases and allergy is also set forth.