发明名称 |
A CANCER DIAGNOSTIC METHOD BASED UPON DNA METHYLATION DIFFERENCES |
摘要 |
There is disclosed a cancer diagnostic method based upon DNA methylation differences at specific CpG sites. As set forth in the Figure, the method comprises bisulfite treatment of DNA, followed by methylation-sensitive single nucleotide primer extension (Ms-SNuPE) for determination of strand-specific methylation status at cytosine residues.
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申请公布号 |
WO9856952(A1) |
申请公布日期 |
1998.12.17 |
申请号 |
WO1998US11896 |
申请日期 |
1998.06.09 |
申请人 |
UNIVERSITY OF SOUTHERN CALIFORNIA |
发明人 |
GONZALGO, MARK, L.;JONES, PETER, A.;LIANG, GANGING |
分类号 |
C07H21/00;C07H21/02;C07H21/04;C12P19/34;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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