发明名称 |
INHIBITORS OF beta -LACTAMASES AND USES THEREFOR |
摘要 |
The invention provides novel non- beta -lactam inhibitors of beta -lactamases. In particular, the invention provides such inhibitors which are boronic acids of formula (1) which is set forth in the specification. These compounds may be used with beta -lactam antibiotics to treat beta -lactam-antibiotic-resistant bacterial infections. These compounds are also antibacterial by themselves. Finally, the invention provides a pharmaceutical composition comprising these compounds. |
申请公布号 |
WO9856392(A1) |
申请公布日期 |
1998.12.17 |
申请号 |
WO1998US12096 |
申请日期 |
1998.06.12 |
申请人 |
NORTHWESTERN UNIVERSITY |
发明人 |
WESTON, GRADY, SCOTT;SHOICHET, BRIAN, K. |
分类号 |
A61K31/69;A61K31/18;A61K31/34;A61K31/38;A61K31/40;A61K31/405;A61K31/43;A61K31/545;A61K33/22;A61P31/04;A61P43/00 |
主分类号 |
A61K31/69 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|