摘要 |
<p>A process for the preparation of 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid and the salts thereof of formula (I), which comprises the following steps: a) carboxymethylation reaction of a suitable precursor in water, with a haloacetic acid, b) hydrolysis reaction in basic conditions by addition of the base added at the previous step.</p> |