Lipopeptides from actinoplanes sp. endowed with pharmacological activity, process for their preparation and their use

摘要

The invention relates to lipopeptides with very homologous amino-acid sequences but different fatty acid residues (lipid portion) which are synthesised by Actinoplanes sp. during fermentation and released into the culture medium, to a process for isolating the lipopeptides from the culture medium and for purifying them, to the use of the lipopeptides as pharmacological agents, in particular against Gram-positive bacteria, and to Actinoplanes sp. DSM 7358 for the preparation of the abovementioned lipopeptides.