| 发明名称 |
Method of peptide synthesis |
| 摘要 |
The present invention relates to a process for forming an N- alpha -amino protected amino acid fluoride in situ by reacting an N- alpha -amino protected amino acid with an ionic fluoride salt in the presence of a peptide coupling agent. It is also directed to the use of the amino acid fluoride thus formed in peptide synthesis.
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| 申请公布号 |
US5849954(A) |
申请公布日期 |
1998.12.15 |
| 申请号 |
US19960588187 |
申请日期 |
1996.01.18 |
| 申请人 |
RESEARCH CORPORATION TECHNOLOGIES, INC. |
发明人 |
CARPINO, LOUIS A.;IONESOU, DUMITRU |
| 分类号 |
C07F9/06;C07F9/54;C07K1/08;C07K1/10;C07K5/06;C07K5/078;C07K5/087;C07K5/107;C07K7/06;C07K14/00;(IPC1-7):C07F9/02;C01B7/00 |
主分类号 |
C07F9/06 |
| 代理机构 |
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