Microorganism of genus chrysosporium for use in preparing farnesyl transferase inhibitors

摘要

PCT No. PCT/FR96/00089 Sec. 371 Date Aug. 8, 1997 Sec. 102(e) Date Aug. 8, 1997 PCT Filed Jan. 19, 1996 PCT Pub. No. WO96/25512 PCT Pub. Date Aug. 22, 1996A Chrysosporium strain No. CBS 123.95, mutants and derivatives thereof, and a method for preparing non-peptide compounds using said strain, are disclosed. Novel compounds of general formula (I), pharmaceutical compositions containing same, and the use of said compounds in anticancer treatments, are also disclosed.