发明名称 Pharmaceutical composition and method for modulating the immune reaction
摘要 Pharmaceutical compositions for the modulation of the immune reaction of warm blooded animals that are derivatives of the 2-oxindole-3-acetic acid or the 2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid are described, and whereby the derivatives can optionally be in an equilibrium with each other. The derivatives included in the pharmaceutical compositions comprise those compounds which are already described in the literature and also new compounds. Furthermore, new derivatives of the the 2-oxindole-3-acetic acid and the 2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid are described, particularly also the the pure antipodes of the mixture of enantiomeres of the 2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid.
申请公布号 US5849756(A) 申请公布日期 1998.12.15
申请号 US19950450491 申请日期 1995.05.26
申请人 CERBIOS-PHARMA SA 发明人 BURGER, ULRICH;JATON, JEAN-CLAUDE;MARAZZA, FABRIZIO;LEWENSTEIN, ARI;SIROTNAK, FRANCIS M.
分类号 A61K31/40;A61K31/403;A61K31/404;A61K31/405;A61K31/47;A61K31/4704;A61P37/02;A61P37/04;A61P37/06;C07D209/34;C07D215/50;(IPC1-7):C07D209/34 主分类号 A61K31/40
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