发明名称 |
Thiodepsipeptide isolated from a marine actinomycete |
摘要 |
The present invention is directed to a novel depsipeptide has been isolated from a new marine strain L-13-ACM2-092 belonging to the family Micromonosporaceae. Its production by aerobic fermentation under controlled conditions of the strain, and the isolation and purification of PM-93135 are described herein. The compound and the fermentation broth demonstrate significant activity against several cancer cell lines. The compound also shows activity against several gram positive bacteria.
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申请公布号 |
US5849540(A) |
申请公布日期 |
1998.12.15 |
申请号 |
US19970936460 |
申请日期 |
1997.09.24 |
申请人 |
PHARMA MAR, S.A. |
发明人 |
BAZ, JULIA PEREZ;MILLAN, FRANCISCO ROMERO;DE QUESADA, TERESA GARCIA;GRAVALOS, DOLORES GARCIA |
分类号 |
C12N1/20;A61K38/00;C07K7/06;C12R1/29;(IPC1-7):C12P21/00 |
主分类号 |
C12N1/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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