发明名称 DNA fragments of mycobacteria, amplification primers hybridization probes, reagents and method for the detection of mycobacteria
摘要 Nucleotide fragment of DNA, whose nucleotide sequence is included in the gene of the species of the genus Mycobacterium, coding for the 65-kD mycobacterial antigen, containing regions which are homologous in practically all species of the genus Mycobacterium, and at least one species-specific variable region, characterized in that said fragment is chosen from fragments whose nucleotide sequences possess at least 70% homology, and preferably at least 85% homology, with a predetermined sequence or its complementary sequence, said predetermined sequence beginning at nucleotide 438 and ending at nucleotide 751 of said gene coding for said antigen of all species of mycobacteria except for the species M. tuberculosis, M. bovis BCG, M. avium, M. paratuberculosis, M. fortuitum, M. malmoense, M. leprae, M. kansaii and M. marinum.
申请公布号 US5849901(A) 申请公布日期 1998.12.15
申请号 US19960698948 申请日期 1996.08.16
申请人 BIO MERIEUX 发明人 MABILAT, CLAUDE;PECHERE, JEAN-CLAUDE
分类号 A61K39/00;C07K14/35;C12N15/31;C12P21/08;C12Q1/68;(IPC1-7):C07H21/04 主分类号 A61K39/00
代理机构 代理人
主权项
地址