发明名称 |
Modified human C3 proteins |
摘要 |
Narrative complement pathway proteins modified such that the protein is capable of forming a stable C3 convertase. Preferably the modified protein is a modified human C3 protein. DNA sequences encoding such proteins are also provided, together with DNA constructs. Conjugates comprising such proteins and a specific binding moiety, for example an antibody, are also described, as are uses of such proteins and/or conjugates in therapy.
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申请公布号 |
US5849297(A) |
申请公布日期 |
1998.12.15 |
申请号 |
US19970793126 |
申请日期 |
1997.02.07 |
申请人 |
IMUTRAN LIMITED |
发明人 |
HARRISON, RICHARD ALEXANDER;FARRIES, TIMOTHY CHARLES |
分类号 |
C12N15/09;A61K38/00;A61K38/17;A61K38/46;A61K38/48;A61K39/395;A61K47/48;A61K48/00;A61P37/00;C07K14/47;C12N5/00;C12N5/10;C12N9/48;C12N9/64;C12N15/12;C12N15/57;C12P21/02;C12R1/91;(IPC1-7):C07K16/46;C07K14/745;A61K38/36 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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