发明名称 STABLE PARTICLE IN LIQUID FORMULATIONS
摘要 A stable particle in liquid formulation comprising a discontinuous phase of microparticles is suspended in a continuous phase which is a non-aqueous liquid, preferably biocompatible in which the microparticles are insoluble. The microparticles comprise finely powdered sugar glass, such as trehalose, palatnit, glucopyranosyl sorbitol, glucopyranosyl mannitol, lactitol and monosaccharide alcohols, such as mannitol and inositol, holding at least one biomolecular product, the biomolecular product in the sugar glass either being in stable solid solution or being itself in suspension in the sugar glass.
申请公布号 WO9841188(A3) 申请公布日期 1998.12.10
申请号 WO1998GB00817 申请日期 1998.03.18
申请人 EASTBRIDGE LIMITED;ROSER, BRUCE, JOSEPH;SEN, SHEVANTI, DEVIKA 发明人 ROSER, BRUCE, JOSEPH;SEN, SHEVANTI, DEVIKA
分类号 C12N15/09;A61K9/00;A61K9/10;A61K9/14;A61K9/16;A61K9/50;A61K38/00;A61K38/18;A61K38/43;A61K38/46;A61K39/395;A61K47/14;A61K47/24;A61K47/26;A61K47/34;C07K14/505;C12N9/16;C12N9/96 主分类号 C12N15/09
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